Blar i forfatter "Akhatov, Nurlan"

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    • Effects of morphine or ketamine in rats with asphyxial cardiac arrest: a pilot study 

      Kuklin, Vladimir; Kondratyev, Timofey; Konkayeva, Maya; Akhatov, Nurlan; Sovershaev, Mikhail; Konkayev, Aidos; Tveita, Torkjel (Conference object; Konferansebidrag, 2017-05-06)
      Acute hypoxia results in uncontrolled release of glutamate and the consequent stimulation of N-methyl-D-aspartate (NMDA) receptors, which affects the whole ionic homeostasis and finally activates apoptosis of neurons. A potential therapeutic approach to prevent this sequence of events is a blockade of NMDA receptors. Meanwhile, in different models of acute hypoxia, activation of delta-opioid ...

    • The influences of morphine or ketamine pre-treatment on hemodynamic, acid-base status, biochemical markers of brain damage and early survival in rats after asphyxial cardiac arrest 

      Kuklin, Vladimir; Akhatov, Nurlan; Kondratiev, Timofei; Konkayev, Aidos; Baigenzhin, Abai K.; Konkayeva, Maiya; Karibekov, Temirlan; Barlow, Nicholas; Tveita, Torkjel; Dahl, Vegard (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-20)
      <i>Background</i> - In different models of hypoxia, blockade of opioid or N-methyl-D-aspartate (NMDA) receptors shows cardio- and neuroprotective effects with a consequent increase in animal survival. The aim of the study was to investigate effects of pre-treatment with Morphine or Ketamine on hemodynamic, acid-base status, early survival, and biochemical markers of brain damage in a rat model of ...